PDL1 EXPRESSION IS A POOR-PROGNOSIS FACTOR IN SOFT-TISSUE SARCOMAS

PDL1 expression is a poor-prognosis factor in soft-tissue sarcomas

Soft-tissue sarcomas (STS) are a group of rare, Napkin Set heterogeneous, and aggressive tumors, with high metastatic risk and relatively few efficient systemic therapies.In the quest for new treatments, the immune system represents an attractive therapeutic target.Recently, PD1/PDL1 inhibitors showed very promising results in patients with solid t

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Fatty acid metabolization and insulin regulation prevent liver injury from lipid accumulation in Himalayan marmots

Summary: Fat storage and weight gain are dominant traits for hibernating mammals.However, excessive fat accumulation may cause liver damage.Here, we explore the lipid accumulation and metabolic processes of the Himalayan marmot (Marmota himalayana), a hibernating rodent species.We find that the unsaturated fatty acid (UFA) content in food was consi

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Heat Transfer Performance of a Novel Multi-Baffle-Type Heat Sink

A new type of multi-baffle-type heat sink is proposed in this paper.The heat-transfer coefficient and pressure drop penalty of the employed Napkin Set six heat sink models are numerically investigated under five different inlet velocities.It is shown that Model 6 (M6) has excellent heat transfer performance as its heat-transfer coefficient reaches

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